Regulation of Skeletal Muscle Glucose Transport and Glucose Metabolism by Exercise Training

Nutrients. 2019 Oct 12;11(10):2432. doi: 10.3390/nu11102432.

Abstract

Aerobic exercise training and resistance exercise training are both well-known for their ability to improve human health; especially in individuals with type 2 diabetes. However, there are critical differences between these two main forms of exercise training and the adaptations that they induce in the body that may account for their beneficial effects. This article reviews the literature and highlights key gaps in our current understanding of the effects of aerobic and resistance exercise training on the regulation of systemic glucose homeostasis, skeletal muscle glucose transport and skeletal muscle glucose metabolism.

Keywords: GLUT; SGLT; aerobic exercise; blood glucose; functional overload; hexokinase; insulin resistance; resistance exercise; type 2 diabetes; weightlifting.

Publication types

  • Review

MeSH terms

  • Biological Transport
  • Exercise / physiology*
  • Glucose / metabolism*
  • Homeostasis
  • Humans
  • Muscle, Skeletal / metabolism*

Substances

  • Glucose