5-ALA PDT successfully treats facial hidradenitis suppurativa-induced severe hypertrophic scar

Zhe-Wen Zhou; Xiao-Dong Chen; Xiao-Yan Wu

doi:10.1016/j.pdpdt.2019.10.008

5-ALA PDT successfully treats facial hidradenitis suppurativa-induced severe hypertrophic scar

Photodiagnosis Photodyn Ther. 2019 Dec:28:343-345. doi: 10.1016/j.pdpdt.2019.10.008. Epub 2019 Oct 12.

Authors

Zhe-Wen Zhou¹, Xiao-Dong Chen², Xiao-Yan Wu³

Affiliations

¹ Department of dermatology and venereology, Nantong University Affiliated Hospital, No. 20 Xisi Road, Nantong 226001, Jiangsu, China(1). Electronic address: zhouzhewen0715@163.com.
² Department of dermatology and venereology, Nantong University Affiliated Hospital, No. 20 Xisi Road, Nantong 226001, Jiangsu, China(1). Electronic address: dermatochen@163.com.
³ Department of dermatology and venereology, Nantong University Affiliated Hospital, No. 20 Xisi Road, Nantong 226001, Jiangsu, China(1). Electronic address: wuxiaoyannt@126.com.

PMID: 31614224
DOI: 10.1016/j.pdpdt.2019.10.008

Abstract

Hidradenitis suppurativa (HS) is a type of chronic suppurative inflammatory reaction of the hair follicles characterized by recurrent dermal abscesses, sinus tracts and scars. In this report, one case of severe hypertrophic scar induced by facial HS achieved resolution of skin lesions after combined treatment with high concentration single-dose 5-aminolevulinic acid photodynamic therapy (5-ALA PDT). No recurrence was observed up to eleven months of follow-up. The 5-ALA PDT based treatment could improve the severe hypertrophic scar induced by HS in an effective and safe manner.

Keywords: 5-aminolevulinic acid photodynamic therapy; Hidradenitis suppurativa; Hypertrophic scar.

Publication types

Case Reports

MeSH terms

Adult
Aminolevulinic Acid / therapeutic use*
Cicatrix, Hypertrophic / drug therapy*
Hidradenitis Suppurativa / drug therapy*
Humans
Male
Photochemotherapy / methods*
Photosensitizing Agents / therapeutic use*

Substances

Photosensitizing Agents
Aminolevulinic Acid