Circ-RPL15: a plasma circular RNA as novel oncogenic driver to promote progression of chronic lymphocytic leukemia

Zijuan Wu; Handong Sun; Wenjie Liu; Huayuan Zhu; Jianxin Fu; Chuang Yang; Lei Fan; Li Wang; Yanfeng Liu; Wei Xu; Jianyong Li; Hui Jin

doi:10.1038/s41375-019-0594-6

Circ-RPL15: a plasma circular RNA as novel oncogenic driver to promote progression of chronic lymphocytic leukemia

Leukemia. 2020 Mar;34(3):919-923. doi: 10.1038/s41375-019-0594-6. Epub 2019 Oct 14.

Authors

Zijuan Wu^#^{1

2

3}, Handong Sun^#⁴, Wenjie Liu^#^{1

2

3}, Huayuan Zhu^{1

2

3}, Jianxin Fu^{1

2

3}, Chuang Yang⁴, Lei Fan^{1

2

3}, Li Wang^{1

2

3}, Yanfeng Liu⁵, Wei Xu^{1

2

3}, Jianyong Li^{6

7

8}, Hui Jin^{9

10

11}

Affiliations

¹ Department of Hematology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China.
² Key Laboratory of Hematology of Nanjing Medical University, 210029, Nanjing, China.
³ Collaborative Innovation Center for Cancer Personalized Medicine, 210029, Nanjing, China.
⁴ Department of Breast Surgery, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, 210029, Nanjing, China.
⁵ Department of Hematology, Qilu hospital, Shandong University, 250012, Jinan, China.
⁶ Department of Hematology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China. lijianyonglm@126.com.
⁷ Key Laboratory of Hematology of Nanjing Medical University, 210029, Nanjing, China. lijianyonglm@126.com.
⁸ Collaborative Innovation Center for Cancer Personalized Medicine, 210029, Nanjing, China. lijianyonglm@126.com.
⁹ Department of Hematology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, China. jinzi817@live.cn.
¹⁰ Key Laboratory of Hematology of Nanjing Medical University, 210029, Nanjing, China. jinzi817@live.cn.
¹¹ Collaborative Innovation Center for Cancer Personalized Medicine, 210029, Nanjing, China. jinzi817@live.cn.

^# Contributed equally.

PMID: 31611623
DOI: 10.1038/s41375-019-0594-6

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Biomarkers, Tumor / blood
Carcinogenesis / genetics
Case-Control Studies
Disease Progression
Female
HEK293 Cells
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / blood*
Leukemia, Lymphocytic, Chronic, B-Cell / pathology*
Leukocytes, Mononuclear / cytology
Male
Middle Aged
Mutation
RNA, Circular / blood*
Ribosomal Protein L10 / blood*
Ribosomal Protein L10 / genetics*
Ribosomal Proteins / blood*
Ribosomal Proteins / genetics*
Risk
Treatment Outcome

Substances

Biomarkers, Tumor
RNA, Circular
RPL10 protein, human
RPL15 protein, human
Ribosomal Proteins