Mean Platelet Volume: A Novel Predictor for Bone Erosion in Gouty Arthritis?

Ann Clin Lab Sci. 2019 Sep;49(5):661-665.

Abstract

Objective: Gout is a type of inflammatory arthritis that can be complicated with bone erosion through several inflammatory factors. Mean platelet volume (MPV) is regarded as a marker in many inflammatory disorders, but despite this, the metric has not been used for gout.

Material and methods: This study evaluates the relationship between MPV and bone erosion in patients with gout. In total, 299 patients were evaluated retrospectively, and 120 patients were ultimately included based on inclusion criteria.

Results: Both the duration of this disease and mean platelet volume were related to bone erosion in gout and may be regarded as independent predictors of bone erosion.

Conclusion: These results suggest that mean platelet volume can be a predictor of bone erosion in gout.

Keywords: Arthritis; bone resorption; gouty; mean platelet volume.

Publication types

  • Observational Study

MeSH terms

  • Arthritis / blood*
  • Arthritis / diagnostic imaging
  • Bone and Bones / diagnostic imaging
  • Bone and Bones / pathology*
  • Female
  • Gout / blood*
  • Gout / diagnostic imaging
  • Humans
  • Male
  • Mean Platelet Volume*
  • Middle Aged
  • Multivariate Analysis
  • Regression Analysis