Black phosphorus nanomaterials as multi-potent and emerging platforms against bacterial infections

Microb Pathog. 2019 Dec:137:103800. doi: 10.1016/j.micpath.2019.103800. Epub 2019 Oct 11.

Abstract

Black phosphorus (BP) has attracted research interest due to its excellent physiochemical properties in various biomedical applications. However, challenges remain of establishing BP as a practical nanomaterial platform against bacterial infections caused by hard-to-treat pathogens. This review highlights the novel approaches for functional properties and advantages of BP over currently available two-dimensional nanomaterials for antibacterial activity. The latest research findings regarding BP for antibacterial activity, potential as alternative antibacterial approach to current antibiotics, and its promise for the future platform are also considered. We believe that our discussions and perspectives on current topics will provide researchers with an up-to-date and handy reference to apply BP as a beneficial nanostructured biomaterial to the human health against various bacterial infections.

Keywords: Antibacterial activity; Biocompatibility; Biodegradability; Black phosphorus; Functional properties; Infectious diseases; Multidrug resistance; Stability.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / administration & dosage*
  • Anti-Bacterial Agents / chemistry
  • Bacteria / drug effects
  • Bacterial Infections / drug therapy*
  • Humans
  • Nanostructures / administration & dosage
  • Nanostructures / chemistry*
  • Phosphorus / administration & dosage*
  • Phosphorus / chemistry

Substances

  • Anti-Bacterial Agents
  • Phosphorus