How can microsphere-mediated delivery of small molecules serve as a novel tool for engineering tissues from stem cells?

Ther Deliv. 2019 Nov;10(11):671-674. doi: 10.4155/tde-2019-0071. Epub 2019 Oct 14.

Author

Stephanie Michelle Willerth¹

Affiliation

¹ Department of Mechanical Engineering & Division of Medical Sciences, University of Victoria; School of Biomedical Engineering & International Collaboration on Repair Discoveries, University of British Columbia, Victoria, BC, V8W 2Y2 Canada; Vancouver, BC, V5Z 1M9, Canada.

PMID: 31608826
DOI: 10.4155/tde-2019-0071

No abstract available

Keywords: biomaterial; controlled release; drug delivery; microsphere; regenerative medicine; tissue engineering.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Cell Differentiation / drug effects
Delayed-Action Preparations / administration & dosage
Drug Compounding / methods
Drug Delivery Systems / methods*
Humans
Induced Pluripotent Stem Cells / drug effects
Induced Pluripotent Stem Cells / physiology*
Microspheres*
Morpholines / administration & dosage
Morpholines / pharmacokinetics
Pregnenediones / administration & dosage
Pregnenediones / pharmacokinetics
Purines / administration & dosage
Purines / pharmacokinetics
Regenerative Medicine
Tissue Engineering / methods*
Tretinoin / administration & dosage
Tretinoin / pharmacokinetics

Substances

Delayed-Action Preparations
Morpholines
Pregnenediones
Purines
Tretinoin
pregna-4,17-diene-3,16-dione
purmorphamine