Hormonal therapy in menopausal transition: implications for improvement of health-related quality of life

Gynecol Endocrinol. 2020 Apr;36(4):327-332. doi: 10.1080/09513590.2019.1676409. Epub 2019 Oct 11.

Abstract

The study aim was to assess scores of the Menopause Rating Scale (MRS) among women who use and desire to use hormonal therapy (HT), as well as to evaluate factors contributing to HT use and desire to use HT among women in menopausal transition. A total of 513 mid-aged women participated in the study. Data were collected using socio-demographic questionnaire, MRS and Beck Depression Inventory. The prevalence of current HT use was 9.7%, while 4.5% of women who did not use HT expressed a desire to start using HT. The MRS cutoff score for HT use was 10.5 and 11.5 among those who desire to use HT. Living in the central city districts, having lower body mass index, younger age at menopause, more gynecological illnesses, and worse MRS were associated with HT use. Living in the central city districts, having fewer births, more gynecological and chronic illnesses and having more depressive symptoms were associated with the desire to use HT. Mid-aged women who perceive their quality of life as poor due to climacteric symptoms should be advised to consider HT to improve their health status and everyday functioning.

Keywords: Menopause; hormone therapy; symptoms; women’s health.

MeSH terms

  • Adult
  • Aged
  • Choice Behavior
  • Climacteric / drug effects*
  • Climacteric / physiology
  • Climacteric / psychology
  • Cross-Sectional Studies
  • Estrogen Replacement Therapy* / psychology
  • Estrogen Replacement Therapy* / statistics & numerical data
  • Female
  • Hot Flashes / epidemiology
  • Humans
  • Menopause / drug effects*
  • Menopause / physiology
  • Menopause / psychology
  • Middle Aged
  • Prevalence
  • Psychiatric Status Rating Scales
  • Quality of Life* / psychology
  • Risk Factors
  • Surveys and Questionnaires