[Advances on network pharmacology in ethnomedicine research]

Zhongguo Zhong Yao Za Zhi. 2019 Aug;44(15):3187-3194. doi: 10.19540/j.cnki.cjcmm.20190711.201.
[Article in Chinese]

Abstract

Ethnomedicine is the precious wealth left by ethnic minorities in their struggle against diseases. It is similar to traditional Chinese medicine in a narrow sense and has the characteristics of multi-component,multi-target and multi-channel synergy. Under the guidance of the theory of ethnomedicine,the combination of ethnomedicine and network pharmacology will help to understand the essence of the prevention and treatment of ethnomedicines in a dynamic and holistic manner. This paper reviews the research progress of network pharmacology applied in ethnomedicine,analyses the problems and challenges existing in the application of network pharmacology in ethnomedicine research at present,such as inaccurate data and information,lack of network analysis platform for effective analysis of dose-effect relationship of chemical constituents and weak basic research of ethnomedicine,and puts forward corresponding prospects.

Keywords: effective material basis; ethnomedicine; mechanism of action; network pharmacology; systems biology.

Publication types

  • Review

MeSH terms

  • Ethnopharmacology*
  • Medicine, Chinese Traditional
  • Medicine, Traditional*