A Guanidine-Based Superbase as Efficient Chemiluminescence Booster

Christina M Geiselhart; Christian W Schmitt; Philipp Jöckle; Hatice Mutlu; Christopher Barner-Kowollik

doi:10.1038/s41598-019-51105-z

A Guanidine-Based Superbase as Efficient Chemiluminescence Booster

Sci Rep. 2019 Oct 10;9(1):14519. doi: 10.1038/s41598-019-51105-z.

Authors

Christina M Geiselhart^{1

2}, Christian W Schmitt³, Philipp Jöckle^{2

4}, Hatice Mutlu^{5

6}, Christopher Barner-Kowollik^{7

8}

Affiliations

¹ Soft Matter Synthesis Laboratory, Institut für Biologische Grenzflächen, Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.
² Macromolecular Architectures, Institut für Technische Chemie und Polymerchemie, Karlsruhe Institute of Technology (KIT), Engesserstraße 18, 76128, Karlsruhe, Germany.
³ School of Chemistry, Physics and Mechanical Engineering and Institute of the Future Environments, Queensland University of Technology (QUT), 2 George Street, QLD, 4000, Brisbane, Australia.
⁴ Molecular Physical Chemistry, Institute of Physical Chemistry, Karlsruhe Institute of Technology (KIT), Fritz-Haber-Weg 2, 76131, Karlsruhe, Germany.
⁵ Soft Matter Synthesis Laboratory, Institut für Biologische Grenzflächen, Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany. hatice.mutlu@kit.edu.
⁶ Macromolecular Architectures, Institut für Technische Chemie und Polymerchemie, Karlsruhe Institute of Technology (KIT), Engesserstraße 18, 76128, Karlsruhe, Germany. hatice.mutlu@kit.edu.
⁷ Macromolecular Architectures, Institut für Technische Chemie und Polymerchemie, Karlsruhe Institute of Technology (KIT), Engesserstraße 18, 76128, Karlsruhe, Germany. christopher.barner-kowollik@kit.edu.
⁸ School of Chemistry, Physics and Mechanical Engineering and Institute of the Future Environments, Queensland University of Technology (QUT), 2 George Street, QLD, 4000, Brisbane, Australia. christopher.barner-kowollik@kit.edu.

Abstract

We introduce the guanidine-based superbase 1,5,7-triaza-bicyclo-[4.4.0]dec-5-ene (TBD) as efficient enabler for chemiluminescence (CL) based on luminol in a simple, ready-to-use two component system. The strong CL is generated by the superbase's properties as peroxidase mimetic and bifunctional coreactant. The herein established concept allows for CL enabling molecules (superbases) to be readily implemented in larger molecular structures, including in polymers.

Publication types

Research Support, Non-U.S. Gov't