Characterization of odorants from baby bottles by headspace solid phase microextraction coupled to gas chromatography-olfactometry-mass spectrometry

Wellington da Silva Oliveira; Jazmin Osorio Monsalve; Cristina Nerin; Marisa Padula; Helena Teixeira Godoy

doi:10.1016/j.talanta.2019.120301

Characterization of odorants from baby bottles by headspace solid phase microextraction coupled to gas chromatography-olfactometry-mass spectrometry

Talanta. 2020 Jan 15:207:120301. doi: 10.1016/j.talanta.2019.120301. Epub 2019 Aug 31.

Authors

Wellington da Silva Oliveira¹, Jazmin Osorio Monsalve², Cristina Nerin³, Marisa Padula⁴, Helena Teixeira Godoy⁵

Affiliations

¹ Department of Food Science, School of Food Engineering, University of Campinas (UNICAMP), Campinas, 13083-862, Brazil. Electronic address: wellingtonoliveira1408@gmail.com.
² Department of Analytical Chemistry, GUIA Group, Aragon Institute of Engineering Research I3A, University of Zaragoza, Zaragoza, 50018, Spain.
³ Department of Analytical Chemistry, GUIA Group, Aragon Institute of Engineering Research I3A, University of Zaragoza, Zaragoza, 50018, Spain. Electronic address: cnerin@unizar.es.
⁴ Packaging Technology Center, Institute of Food Technology (ITAL), Campinas, 13070-178, Brazil.
⁵ Department of Food Science, School of Food Engineering, University of Campinas (UNICAMP), Campinas, 13083-862, Brazil.

PMID: 31594562
DOI: 10.1016/j.talanta.2019.120301

Abstract

A SPME protocol was optimised for the characterization of odorous migrants coming from baby bottles. Considering this, a Plackett-Burman design to select variables and a central composite rotatable design to define the optimal conditions were used. The method proposed by Derringer and Suich was used to simultaneously optimise the responses. After validation, the analytical method was used to characterise volatile migrants from baby bottles made of polypropylene, Tritan and silicone using 50% ethanol as a simulant. 2,4-di-tert-butylphenol was identified in all samples. Forty-five compounds were identified, of which thirty-eight were odorants in silicone baby bottles. Aldehydes were mainly responsible for the unpleasant odour of silicone. Moreover, silicone showed slightly higher volatile organic compounds (%) than recommended. Odours from ketones, benzophenone derivatives and alcohols were also detected by GC-O-MS, however below the LOQ obtained in the MS detector. All migration data were below the specific migration limits.

Keywords: Migration; Olfactometry; Plackett-burman; Silicone baby bottles; Volatile organic compounds.