Fabrication of Concentric Carbon Nanotube Rings and Their Application on Regulating Cell Growth

Hu Li; Luming Zhao; Weibo Zhu; Xuecheng Qu; Chan Wang; Ruping Liu; Yubo Fan; Zhou Li

doi:10.1021/acsomega.9b02449

Fabrication of Concentric Carbon Nanotube Rings and Their Application on Regulating Cell Growth

ACS Omega. 2019 Sep 18;4(14):16209-16216. doi: 10.1021/acsomega.9b02449. eCollection 2019 Oct 1.

Authors

Hu Li¹, Luming Zhao^{2

3}, Weibo Zhu⁴, Xuecheng Qu^{2

3}, Chan Wang^{2

3}, Ruping Liu⁴, Yubo Fan^{1

5}, Zhou Li^{2

3}

Affiliations

¹ Beijing Advanced Innovation Centre for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Chinese Education Ministry, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.
² CAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-Nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083, China.
³ College of Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing 100049, China.
⁴ School of Printing and Packaging Engineering, Beijing Institute of Graphic Communication, Beijing 102600, China.
⁵ National Research Center for Rehabilitation Technical Aids, Beijing 100176, China.

Abstract

The carbon nanotube (CNT) pattern plays an important role in various electronic devices and biological fields for its superior conductivity and biocompatibility. Herein, we fabricated regularly arranged concentric multiwalled carbon nanotube (MWCNT) rings in a Petri dish by evaporation-driven self-assembly technology. By adjusting the dispersion ratio, heating temperature, and solution volume, various MWCNT rings with different shapes and morphologies were obtained. The variation law of ring radius, formation range, and ring numbers was processed with statistical analysis. With fine adjustment of parameters, the control of desired MWCNT rings can be achieved for further scientific researches. By culturing L929 cells with these rings, oriented cell growth along the rings was achieved, which is of significance for cell regulation, tissue repairing, and related biological applications.