Asthma and Chronic Obstructive Pulmonary Disease Associated With Occupational Exposure in Dairy Farmers - Importance of Job Exposure Matrices

Saso Stoleski; Jordan Minov; Jovanka Karadzinska-Bislimovska; Dragan Mijakoski; Aneta Atanasovska; Dragana Bislimovska

doi:10.3889/oamjms.2019.630

Asthma and Chronic Obstructive Pulmonary Disease Associated With Occupational Exposure in Dairy Farmers - Importance of Job Exposure Matrices

Open Access Maced J Med Sci. 2019 Jul 28;7(14):2350-2359. doi: 10.3889/oamjms.2019.630. eCollection 2019 Jul 30.

Authors

Saso Stoleski¹, Jordan Minov¹, Jovanka Karadzinska-Bislimovska¹, Dragan Mijakoski¹, Aneta Atanasovska¹, Dragana Bislimovska¹

Affiliation

¹ Institute for Occupational Health of Republic of Macedonia, WHO Collaborating Center, Galen Collaborating Center, Skopje, Republic of Macedonia.

Abstract

Aim: To evaluate the prevalence of chronic respiratory symptoms, lung function impairment, and chronic obstructive respiratory diseases in dairy farmers. Our objective is to then examine their relation to exposure duration and to explore the usefulness of job exposure matrices as tools for exposure assessment, and predictors for respiratory health impairment.

Methods: A cross-sectional study was performed, including 83 dairy farmers (mean age: 52.6 ± 8.7 years; mean exposure duration: 23.7 ± 7.6 years) and 80 office workers as a control group (mean age: 52.7 ± 8.2 years) matched for age, smoking habits, and socioeconomic status. Methods of evaluating examined subjects included a questionnaire on respiratory symptoms in the last 12 months, spirometry and histamine challenge, as well as the use of job exposure matrices (JEM).

Results: Dairy farmers had a significantly higher prevalence of cough (38.5), phlegm (27.7%), and wheezing (21.7%), than controls (p < 0.05). All mean baseline spirometric parameters were lower in dairy farmers compared to the controls, but statistical significance was confirmed only for MEF25, MEF50, and MEF75% (p = 0.010, p = 0.001, and p = 0.004, respectively). The prevalence of bronchial hyperresponsiveness, asthma, and chronic obstructive pulmonary disease was higher in dairy farmers but without statistical significance. JEM were useful tools for exposure assessment and predictors of factors for asthma and COPD development.

Conclusion: The results suggest that occupational exposure among crop farmers is associated with a higher prevalence of respiratory symptoms, lung function impairment, and a higher prevalence of chronic respiratory diseases. JEM showed good potential for farming exposure evaluation and promoted their applicability within the diagnostic algorithm focused on respiratory health assessment.

Keywords: Chronic obstructive lung diseases; Farming; Job exposure; Questionnaire; Respiratory symptoms; Spirometry.