Unconventional Tissue Engineering Materials in Disguise

Trends Biotechnol. 2020 Feb;38(2):178-190. doi: 10.1016/j.tibtech.2019.07.014. Epub 2019 Oct 4.

Abstract

Tissue engineering faces a recurring challenge in the transformation of biomaterials into 3D constructs that mimic the biological, chemical, and mechanical features of native tissues. Some of the conventional approaches can be sophisticated and involve extensive material processing and high-cost fabrication procedures. Despite tremendous strides in biomaterials discovery and characterization, the functional and manufacturing limitations have led to the innovation of novel biomimetic techniques that borrow from nature, human-made commodities, and other parts of life to overcome the challenges in tissue engineering and regenerative medicine. This review explores engineering strategies that involve unusual materials for improved functionality, scalability, sustainability, and cost-efficiency. The biomaterials discussed are globally accessible resources and can serve across a wide spectrum of biomedical research areas.

Keywords: biomaterials; regenerative medicine; scaffolds; tissue engineering.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Aquatic Organisms
  • Biocompatible Materials / chemistry*
  • Egg Shell / chemistry
  • Humans
  • Ice
  • Paper
  • Plants / chemistry
  • Porifera
  • Regenerative Medicine / methods
  • Textiles
  • Tissue Engineering / methods*
  • Tissue Scaffolds

Substances

  • Biocompatible Materials
  • Ice