Anti-HMGCR myopathy following acute Epstein-Barr virus infection

Muscle Nerve. 2020 Jan;61(1):E5-E8. doi: 10.1002/mus.26729. Epub 2019 Oct 22.

Authors

Affiliations

¹ Department of Neurology, Kitasato University School of Medicine, Sagamihara, Japan.
² Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Japan.
³ Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan.

PMID: 31588573
DOI: 10.1002/mus.26729

No abstract available

Keywords: Epstein-Barr virus; acute viral infection; anti-HMGCR antibody; immune-mediated necrotizing myopathy; immunotherapy; muscle biopsy.

Publication types

Case Reports

MeSH terms

Adult
Anti-Inflammatory Agents / therapeutic use
Autoantibodies
Autoimmune Diseases / diagnostic imaging
Autoimmune Diseases / drug therapy
Autoimmune Diseases / etiology*
Epstein-Barr Virus Infections / complications*
Epstein-Barr Virus Infections / diagnostic imaging
Epstein-Barr Virus Infections / drug therapy
Female
Hamstring Muscles / diagnostic imaging
Hamstring Muscles / pathology
Humans
Hydroxymethylglutaryl CoA Reductases / immunology*
Magnetic Resonance Imaging
Methylprednisolone / therapeutic use
Muscle Weakness
Muscular Diseases / diagnostic imaging
Muscular Diseases / drug therapy
Muscular Diseases / etiology*
Treatment Outcome

Substances

Anti-Inflammatory Agents
Autoantibodies
HMGCR protein, human
Hydroxymethylglutaryl CoA Reductases
Methylprednisolone