Hickam's dictum: Angiosarcoma-to-meningioma metastasis

Neuropathology. 2019 Dec;39(6):447-451. doi: 10.1111/neup.12591. Epub 2019 Oct 4.

Abstract

Tumor-to-tumor metastasis is a seldom reported phenomenon whereby a neoplasm seeds within another histologically distinct tumor, with only 84 cases documented in the literature. We hereby describe the case of a 95-year-old woman who died of widespread metastases identified as a primary hepatic angiosarcoma on autopsy, and the interesting finding of a seeding foci within a dural meningioma. Although meningiomas are the most common intracranial neoplasms to harbor such a phenomenon, this is to our knowledge the first case where an angiosarcoma was identified as the donor tumor.

Keywords: angiosarcoma; meningioma; neuroimaging; pathology; tumor-to-tumor metastasis.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Fatal Outcome
  • Female
  • Hemangiosarcoma / diagnostic imaging*
  • Humans
  • Liver Neoplasms / diagnostic imaging*
  • Liver Neoplasms / secondary*
  • Meningeal Neoplasms / diagnostic imaging*
  • Meningioma / diagnostic imaging*