Discovery of a macrocyclic γ-AApeptide binding to lncRNA GAS5 and its therapeutic implication in Type 2 diabetes

Future Med Chem. 2019 Sep;11(17):2233-2235. doi: 10.4155/fmc-2019-0148.
No abstract available

Keywords: GAS5; Type 2 diabetes mellitus; insulin; long noncoding RNAs; macrocyclic γ-AApeptide.

Publication types

  • Editorial

MeSH terms

  • Blood Glucose / metabolism
  • Diabetes Mellitus, Type 2 / therapy*
  • Gene Expression Regulation
  • Humans
  • Insulin / metabolism
  • MicroRNAs / metabolism
  • Peptide Library
  • Peptides, Cyclic / metabolism*
  • Peptides, Cyclic / therapeutic use
  • Promoter Regions, Genetic
  • RNA, Long Noncoding / metabolism*
  • Receptor, Insulin / genetics*

Substances

  • Blood Glucose
  • Insulin
  • MicroRNAs
  • Peptide Library
  • Peptides, Cyclic
  • RNA, Long Noncoding
  • Receptor, Insulin