Diffuse Skeletal Uptake on 18F-Fluoro-2-Deoxy-d-glucose Positron Emission Tomography/Computed Tomography Scan in a Patient with Acute Lymphoblastic Leukemia: A Typical Superscan Pattern Resembling NaF Positron Emission Tomography Scan

Abbas Yousefi-Koma; Yaser Shiravand; Mohsen Qutbi

doi:10.4103/ijnm.IJNM_106_19

Diffuse Skeletal Uptake on ¹⁸F-Fluoro-2-Deoxy-d-glucose Positron Emission Tomography/Computed Tomography Scan in a Patient with Acute Lymphoblastic Leukemia: A Typical Superscan Pattern Resembling NaF Positron Emission Tomography Scan

Indian J Nucl Med. 2019 Oct-Dec;34(4):326-328. doi: 10.4103/ijnm.IJNM_106_19.

Authors

Abbas Yousefi-Koma¹, Yaser Shiravand², Mohsen Qutbi²

Affiliations

¹ Chronic Respiratory Diseases Research Center (CRDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
² Department of Nuclear Medicine, Taleghani Educational Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract

A 65-year-old patient with acute lymphoblastic leukemia presented for an ¹⁸fluoro-2-deoxy-d-glucose positron emission tomography computed tomography (¹⁸FDG PET) after several courses of chemotherapy for metastatic evaluation. Unexpectedly, on ¹⁸FDG PET scan, no discernible uptake was observed in the visceral organs, but instead, the skeleton/bone marrow showed homogenously intense metabolic activity. The distribution of ¹⁸FDG observed on the scan was remarkably similar to that on the NaF PET scan, indicating a superscan appearance.

Keywords: 18 fluoro-2-deoxy-d-glucose positron emission tomography computed tomography; acute lymphoblastic leukemia; bone marrow; diffuse uptake; skeleton; superscan.