Influenza virus B-associated hemophagocytic lymphohistiocytosis

Jackson Gao; Jeremiah Pasion; Gabriela Sanchez-Petitto; Jennie Law

doi:10.4081/hr.2019.8268

Influenza virus B-associated hemophagocytic lymphohistiocytosis

Hematol Rep. 2019 Sep 18;11(3):8268. doi: 10.4081/hr.2019.8268.

Authors

Jackson Gao¹, Jeremiah Pasion², Gabriela Sanchez-Petitto³, Jennie Law³

Affiliations

¹ Department of Medicine.
² Department of Pathology, University of Maryland School of Medicine, Baltimore, MD.
³ University of Maryland School of Medicine, Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA.

Abstract

This original report describes the diagnosis and management of a male with hemophagocytic lymphohistiocytosis (HLH) triggered by influenza B virus infection. The patient was diagnosed with HLH- 2004 clinical criteria and a bone marrow biopsy demonstrating hemophagocytes. Therapy consisted of etoposide and dexamethasone while monitoring hemoglobin and platelet levels. To enable early recognition and prompt treatment for this disease, physicians should be aware of this association.

Keywords: Hemophagocytic Lymphohistiocytosis; Influenza B virus; hemophagocyte.

Grants and funding

Funding: none.