New chemical constituent from the stem of Cuscuta reflexa Roxb. and its biological activities

Nat Prod Res. 2021 Jul;35(14):2429-2432. doi: 10.1080/14786419.2019.1669033. Epub 2019 Oct 3.

Abstract

Chemical investigations on the stem of Cuscuta reflexa Roxb. (Convolvulaceae) led to the isolation of one new compound characterised as 3',4'-dimethoxy-1-phenyl-1α, 2-ethanediol (1), along with eight known compounds as tridecanyl palmitate, palmitic acid, n-pentatriacontane, n-triacont-21, 27-dien-1-ol, kaempherol, chlorogenic acid, 5,7-dimethoxyapigenin and quercitin. The chemical structures were established with the help of physical, chemical and spectroscopic methods. The antimicrobial potential of the new compound (1) was evaluated against three bacterial and three fungal pathogenic strain and showed significant activities.

Keywords: Cuscuta reflexa; Convolvulaceae; antimicrobial activity; new compound; spectroscopic analysis.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Antifungal Agents / pharmacology
  • Carbon-13 Magnetic Resonance Spectroscopy
  • Cuscuta / chemistry*
  • Microbial Sensitivity Tests
  • Phytochemicals / chemistry
  • Phytochemicals / pharmacology*
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Plant Stems / chemistry*
  • Proton Magnetic Resonance Spectroscopy

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Phytochemicals
  • Plant Extracts