Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study

Cardiovasc Intervent Radiol. 2020 Feb;43(2):331-338. doi: 10.1007/s00270-019-02347-x. Epub 2019 Oct 2.

Abstract

Purpose: To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI).

Materials and methods: Imaging of eight tracer-filled, stented vessel phantoms and a tracer-filled, non-stented reference phantom for each diameter was performed on a preclinical MPI scanner: eight commercially available coronary stents of different dimensions (diameter: 3-4 mm; length: 11-38 mm) and materials (stainless steel, platinum-chromium) were implanted into silicone vessel phantoms. For comparison, all vessel phantoms were also visualized by MRI and CT. Two radiologists assessed the images regarding stent-induced artifacts using a 5-point grading scale.

Results: The visualization of all stented vessel phantoms was achieved without stent-induced artifacts with MPI. In contrast, MRI and CT images revealed multiform stent-induced artifacts.

Conclusion: Given its clinical introduction, MPI has the potential to overcome the disadvantages of MRI and CT concerning the visualization of the stent lumen.

Keywords: Artifacts; Computed tomography; Magnetic particle imaging; Magnetic resonance imaging; Stents.

MeSH terms

  • Artifacts*
  • Image Processing, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods
  • Magnetite Nanoparticles*
  • Phantoms, Imaging*
  • Stents*
  • Tomography / methods*
  • Tomography, X-Ray Computed / methods

Substances

  • Magnetite Nanoparticles