Single-cell transcriptomics reveal polyclonal memory T-cell responses in skin with positive abacavir patch test results

J Allergy Clin Immunol. 2019 Nov;144(5):1413-1416.e7. doi: 10.1016/j.jaci.2019.09.013. Epub 2019 Sep 28.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anti-HIV Agents / adverse effects*
  • Anti-HIV Agents / immunology
  • Anti-HIV Agents / therapeutic use
  • Arthralgia
  • CD8-Positive T-Lymphocytes / immunology*
  • Dideoxynucleosides / adverse effects*
  • Dideoxynucleosides / immunology
  • Dideoxynucleosides / therapeutic use
  • Drug Hypersensitivity / diagnosis*
  • Drug Hypersensitivity / etiology
  • Drug-Related Side Effects and Adverse Reactions / diagnosis*
  • Gene Expression Profiling
  • HLA-B Antigens / metabolism
  • Headache
  • Humans
  • Immunologic Memory
  • Lymphocyte Activation
  • Male
  • Myalgia
  • Patch Tests
  • Single-Cell Analysis
  • Skin / immunology*

Substances

  • Anti-HIV Agents
  • Dideoxynucleosides
  • HLA-B Antigens
  • HLA-B*57:01 antigen
  • abacavir