Oral Food Challenges in Infants and Toddlers

Immunol Allergy Clin North Am. 2019 Nov;39(4):481-493. doi: 10.1016/j.iac.2019.07.003.

Abstract

Oral food challenges (OFCs) are an indispensable tool for accurately diagnosing clinically relevant food allergy. Despite perceived concerns, data suggest OFCs, including infant OFCs, are both safe and practical in the clinical setting. The benefits of OFCs can be far reaching and impactful for the patient and parents, with improved quality of life, clarifying unnecessary dietary restrictions, increased social interactions, and reducing fear and anxiety. Demand for OFCs in infants and toddlers will continue to increase in the coming years and board-certified allergists will need to meet these demands by providing appropriate care in a safe and welcoming environment.

Keywords: Anaphylaxis; Epinephrine; Food allergy; Infants; Oral food challenge.

Publication types

  • Review

MeSH terms

  • Allergens / immunology*
  • Animals
  • Child, Preschool
  • Diagnostic Tests, Routine
  • Disease Management
  • Food / adverse effects*
  • Food Hypersensitivity / diagnosis*
  • Food Hypersensitivity / immunology*
  • Humans
  • Immunologic Tests
  • Infant
  • Infant, Newborn
  • Reproducibility of Results

Substances

  • Allergens