En masse discovery of anti-cancer human monoclonal antibodies by de novo assembly of immunoglobulin sequences from transcriptomes and genome sequences of cancer tissues

Cell Mol Immunol. 2019 Dec;16(12):943-945. doi: 10.1038/s41423-019-0299-9. Epub 2019 Sep 27.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antineoplastic Agents, Immunological / therapeutic use*
  • B-Lymphocytes / immunology*
  • Base Sequence / genetics
  • Computational Biology
  • Humans
  • Immunotherapy / methods*
  • Lymphocytes, Tumor-Infiltrating / immunology*
  • Neoplasms / diagnosis
  • Neoplasms / immunology*
  • Receptors, Antigen, B-Cell / genetics*
  • Sequence Analysis, RNA
  • Transcriptome
  • Whole Genome Sequencing

Substances

  • Antineoplastic Agents, Immunological
  • Receptors, Antigen, B-Cell