New Strategies to Overcome Resistance to Chemotherapy and Immune System in Cancer

Chiara Riganti; Marialessandra Contino

doi:10.3390/ijms20194783

New Strategies to Overcome Resistance to Chemotherapy and Immune System in Cancer

Int J Mol Sci. 2019 Sep 26;20(19):4783. doi: 10.3390/ijms20194783.

Authors

Chiara Riganti¹, Marialessandra Contino²

Affiliations

¹ Department of Oncology, Oncological Pharmacology Lab, University of Torino via Santena 5/bis, 10126 Torino, Italy. chiara.riganti@unito.it.
² Department of Pharmacy, University of Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy. marialessandra.contino@uniba.it.

Abstract

MultiDrug resistance (MDR) is a complex phenomenon responsible for multiple cross-resistance towards structurally unrelated drugs and it characterizes almost 70% of solid and haematological tumours at the diagnosis [...].

Keywords: cancer stem-like cells; chemotherapy; immunotherapy; multidrug resistance (MDR).

Publication types

Editorial
Introductory Journal Article

MeSH terms

Antineoplastic Agents / pharmacology*
Antineoplastic Agents / therapeutic use*
Biomarkers
Drug Resistance, Neoplasm* / genetics
Drug Resistance, Neoplasm* / immunology
Humans
Immune System / drug effects*
Neoplasms / drug therapy*
Neoplasms / genetics
Neoplasms / immunology*
Neoplasms / pathology
Neoplastic Stem Cells / drug effects
Neoplastic Stem Cells / immunology
Neoplastic Stem Cells / metabolism

Substances

Antineoplastic Agents
Biomarkers