Objective: The aim of this study was to evaluate the effects of a manual therapy using fascial therapy on joint bleeding, joint pain and joint function in patients with hemophilic ankle arthropathy.
Setting: Hemophilia patient associations.
Design: Randomized, controlled trial, multicenter and intention-to-treat analysis.
Participants: A total of 65 patients with hemophilic ankle arthropathy.
Intervention: The experimental group (n = 33) received one fascial therapy session per week for three weeks. The control group (n = 32) received no treatment.
Outcome measure: The primary outcome was frequency of joint bleeding measured using self-reporting. Secondary outcomes were joint pain (under load-bearing and non-load-bearing conditions) measured using the visual analog scale; joint condition was measured using the Hemophilia Joint Health Score. Outcomes were measured at baseline, posttreatment and after five months of follow-up.
Results: Improvements in the frequency joint bleeding at T0, T1 and T2 were significantly higher in the experimental group (T0: mean (SD) = 1.56 (1.30); T1: mean (SD) = 0.00 (0.00); T2: mean (SD) = 0.27 (0.57)) compared to the control group (T0: mean (SD) = 1.70 (1.78); T1: mean (SD) = 0.05 (0.21); T2: mean (SD) = 0.58 (0.85)). Mean improvement of joint state after the study period was 1.74 points (±1.66) for patients in the experimental group, while the control group exhibited a joint deterioration with 0.43 points (±0.85). Ankle joint pain under load-bearing and non-load-bearing conditions improved in the experimental group with -1.72 (±1.86) and -0.50 (±1.39) points, respectively.
Conclusion: The study showed that fascial therapy is favorable for patients with hemophilic ankle arthropathy.
Keywords: Hemophilia; ankle arthropathy; fascial therapy; physical therapy; randomized clinical trial.