[Vitamin D and Hashimoto's disease]

Małgorzata Jamka; Marek Ruchała; Jarosław Walkowiak

[Vitamin D and Hashimoto's disease]

Pol Merkur Lekarski. 2019 Sep 25;47(279):111-113.

[Article in Polish]

Authors

Małgorzata Jamka¹, Marek Ruchała², Jarosław Walkowiak¹

Affiliations

¹ Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Poland.
² Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poland.

PMID: 31557141

Abstract

It is probably that vitamin D may play an important role in the pathogenesis of Hashimoto's disease. Previous studies have shown a higher incidence of vitamin D deficiencies in patients with Hashimoto's disease compared to healthy subjects. Probably the severity of Hashimoto's disease may affect serum 25-hydroxycholecalciferol (25(OH)D) concentrations. In addition, a negative correlation between serum 25(OH)D concentrations and the level of antithyroid antibodies was observed. Moreover, vitamin D supplementation seems to be effective in reducing the levels of thyroid peroxidase (TPO) antibodies both in patients with deficiency and with normal concentrations of vitamin D. However, further studies are needed to more accurately determine the effect of vitamin D supplementation on the Hashimoto's disease.

Keywords: Hashimoto’s disease; autoimmune thyroiditis; cholecalciferol; vitamin D.

Publication types

Review

MeSH terms

Hashimoto Disease* / complications
Humans
Vitamin D / therapeutic use
Vitamin D Deficiency* / complications
Vitamin D Deficiency* / drug therapy
Vitamins / therapeutic use

Substances

Vitamins
Vitamin D