Overview of Genomic Tools for Circular Visualization in the Next-generation Genomic Sequencing Era

Alisha Parveen; Sukant Khurana; Abhishek Kumar

doi:10.2174/1389202920666190314092044

Overview of Genomic Tools for Circular Visualization in the Next-generation Genomic Sequencing Era

Curr Genomics. 2019 Feb;20(2):90-99. doi: 10.2174/1389202920666190314092044.

Authors

Alisha Parveen¹, Sukant Khurana¹, Abhishek Kumar¹

Affiliation

¹ 1Medical Research Center, Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany; 2Pharmacology Department, Central Drug Research Institute - Lucknow, Uttar Pradesh, India; 3Department of Genetics & Molecular Biology in Botany, Institute of Botany, Christian-Albrechts-University at Kiel, Kiel, Germany.

Abstract

After human genome sequencing and rapid changes in genome sequencing methods, we have entered into the era of rapidly accumulating genome-sequencing data. This has derived the development of several types of methods for representing results of genome sequencing data. Circular genome visual-ization tools are also critical in this area as they provide rapid interpretation and simple visualization of overall data. In the last 15 years, we have seen rapid changes in circular visualization tools after the de-velopment of the circos tool with 1-2 tools published per year. Herein we have summarized and revisited all these tools until the third quarter of 2018.

Keywords: BLAST alignment; Circos; Circular visualization; Data modeling; Genomics; Next-generation sequencing.

Publication types

Review