Diagnosis of spontaneous hyperadrenocorticism in dogs. Part 2: Adrenal function testing and differentiating tests

Michael Bennaim; Robert E Shiel; Carmel T Mooney

doi:10.1016/j.tvjl.2019.105343

Diagnosis of spontaneous hyperadrenocorticism in dogs. Part 2: Adrenal function testing and differentiating tests

Vet J. 2019 Oct:252:105343. doi: 10.1016/j.tvjl.2019.105343. Epub 2019 Jul 27.

Authors

Michael Bennaim¹, Robert E Shiel², Carmel T Mooney²

Affiliations

¹ Section of Small Animal Clinical Studies, School of Veterinary Medicine, University College Dublin, Ireland. Electronic address: michael.bennaim@gmail.com.
² Section of Small Animal Clinical Studies, School of Veterinary Medicine, University College Dublin, Ireland.

PMID: 31554584
DOI: 10.1016/j.tvjl.2019.105343

Abstract

Hyperadrenocorticism is a relatively common endocrine disorder in dogs that has been extensively described. However, its diagnosis remains challenging because there is no true reference standard test, and a myriad factors can affect the diagnostic performance of the commonly used adrenal function tests. Ultimately, the diagnosis is based on a combination of signalment, history and clinical findings, and a variety of diagnostic test results. The second part of this review aims to appraise available data on diagnostic performance of adrenal function tests in naturally occurring canine hyperadrenocorticism.

Keywords: Adrenals; Cortisol; Cushings; Endocrinology; Pituitary.

Publication types

Review

MeSH terms

Adrenal Cortex Function Tests / veterinary*
Adrenocortical Hyperfunction / diagnosis
Adrenocortical Hyperfunction / veterinary*
Adrenocorticotropic Hormone / blood*
Animals
Dog Diseases / blood
Dog Diseases / diagnosis*
Dogs

Substances

Adrenocorticotropic Hormone