Cancer Genetic Counseling-Current Practice and Future Challenges

Cold Spring Harb Perspect Med. 2020 Jun 1;10(6):a036541. doi: 10.1101/cshperspect.a036541.

Abstract

Cancer genetic counseling practice is rapidly evolving, with services being provided in increasingly novel ways. Pretest counseling for cancer patients may be abbreviated from traditional models to cover the elements of informed consent in the broadest of strokes. Genetic testing may be ordered by a cancer genetics professional, oncology provider, or primary care provider. Increasingly, direct-to-consumer testing options are available and utilized by consumers anxious to take control of their genetic health. Finally, genetic information is being used to inform oncology care, from surgical decision-making to selection of chemotherapeutic agent. This review provides an overview of the current and evolving practice of cancer genetic counseling as well as opportunities and challenges for a wide variety of indications in both the adult and pediatric setting.

Publication types

  • Review

MeSH terms

  • Adult
  • Child
  • Genetic Counseling*
  • Genetic Predisposition to Disease
  • Genetic Testing / ethics
  • Genetic Testing / methods*
  • Humans
  • Informed Consent*
  • Models, Theoretical
  • Neoplasms / diagnosis*
  • Neoplasms / genetics*