A "Cat"-astrophic Case of Bartonella henselae infective endocarditis followed by cardiac transplantation salvage therapy

Transpl Infect Dis. 2019 Dec;21(6):e13179. doi: 10.1111/tid.13179. Epub 2019 Oct 6.

Abstract

To our knowledge, no cases of Bartonella henselae endocarditis leading to subsequent heart transplantation salvage therapy have been published. We present a case of a 29-year-old man with cat-inflicted B henselae endocarditis and concurrent worsening heart failure, who then underwent successful heart transplantation 50 days following diagnosis. Treatment and monitoring strategies used in this patient are discussed. Furthermore, we review literature related to heart transplantation salvage therapy for endocarditis due to other intracellular pathogens.

Keywords: Bartonella henselae; heart transplant; infective endocarditis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Aortic Valve / abnormalities
  • Aortic Valve / diagnostic imaging
  • Aortic Valve / microbiology
  • Aortic Valve / surgery
  • Bartonella henselae / isolation & purification*
  • Bartonella henselae / pathogenicity
  • Bicuspid Aortic Valve Disease
  • Bioprosthesis / adverse effects
  • Echocardiography
  • Endocarditis, Bacterial / complications
  • Endocarditis, Bacterial / diagnosis
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / microbiology*
  • Heart Failure / microbiology
  • Heart Failure / surgery*
  • Heart Transplantation*
  • Heart Valve Diseases / surgery
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / instrumentation
  • Humans
  • Male
  • Prosthesis-Related Infections / complications
  • Prosthesis-Related Infections / diagnosis
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / microbiology*
  • Salvage Therapy / methods*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents