Transfusion Reactions: A Case Study of an Ocular Adverse Event During Autologous Transplantation

Clin J Oncol Nurs. 2019 Oct 1;23(5):509-513. doi: 10.1188/19.CJON.509-513.

Abstract

Background: Transfusion of blood products is an integral part of hematopoietic stem cell transplantation. Because of the risk for myelotoxicity during conditioning regimens, adequate transfusion support is needed. Typical signs and symptoms of transfusion reactions include fever, chills, hives, and itching. Uncommon symptoms, such as conjunctival erythema, periorbital itching, erythema, and edema, can also occur.

Objectives: The purpose of this article is to describe atypical transfusion-related reactions in a patient undergoing stem cell transplantation.

Methods: This article presents a case study of a patient with cancer undergoing autologous stem cell transplantation who experienced an adverse ocular reaction following platelet transfusion.

Findings: Ensuring that oncology nurses are proactive in identifying and managing symptoms that can result from atypical transfusion reactions can reduce morbidity and mortality and improve overall patient care outcomes.

Keywords: adverse events; ocular reaction; platelet transfusion; stem cell transplantation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blood Transfusion*
  • Eye Diseases / etiology*
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Male
  • Neoplasms / therapy*
  • Transplantation, Autologous / adverse effects*