Case Studies and Literature Review of Pneumococcal Septic Arthritis in Adults

Emerg Infect Dis. 2019 Oct;25(10):1824-1833. doi: 10.3201/eid2510.181695.

Abstract

We conducted a retrospective study on all cases of pneumococcal septic arthritis (SA) in patients >18 years of age reported to the Picardie Regional Pneumococcal Network in France during 2005-2016. Among 1,062 cases of invasive pneumococcal disease, we observed 16 (1.5%) SA cases. Although SA is uncommon in adult patients, the prevalence of pneumococcal SA in the Picardie region increased from 0.69% during 2005-2010 to 2.47% during 2011-2016 after introduction of the pneumococcal 13-valent conjugate vaccine. We highlight the emergence of SA cases caused by the 23B serotype, which is not covered in the vaccine.

Keywords: France; Streptococcus pneumoniae; bacteria; pneumococcal disease; septic arthritis; vaccines.

Publication types

  • Case Reports
  • Meta-Analysis
  • Review

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Arthritis, Infectious / epidemiology*
  • Arthritis, Infectious / etiology
  • Arthritis, Infectious / microbiology
  • Female
  • France / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Pneumococcal Infections / complications
  • Pneumococcal Infections / epidemiology*
  • Pneumococcal Infections / microbiology
  • Pneumococcal Vaccines / therapeutic use
  • Prevalence
  • Retrospective Studies

Substances

  • Pneumococcal Vaccines