Artificial Signal Transduction across Membranes

Chembiochem. 2019 Oct 15;20(20):2569-2580. doi: 10.1002/cbic.201900254. Epub 2019 Sep 13.

Abstract

A key conundrum in the construction of an artificial cell is to simultaneously maintain a robust physical barrier to the external environment, while also providing efficient exchange of information across this barrier. Biomimicry provides a number of avenues by which such requirements might be met. Herein, we provide a brief introduction to the challenges facing this field and explore progress to date.

Keywords: artificial cells; biomimicry; ion channels; nanotechnology; receptors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Artificial Cells / cytology
  • Artificial Cells / metabolism*
  • Ion Channels / chemistry*
  • Lipid Bilayers / chemistry*
  • Membranes, Artificial
  • Nanopores / ultrastructure*
  • Protein Engineering
  • Receptors, Cell Surface / chemistry*
  • Signal Transduction
  • Synthetic Biology

Substances

  • Ion Channels
  • Lipid Bilayers
  • Membranes, Artificial
  • Receptors, Cell Surface