Multi-phase detection of antioxidants using surface-enhanced Raman spectroscopy with a gold nanoparticle-coated fiber

Qin Tu; Zhuangsheng Lin; Jinning Liu; Haochen Dai; Tianxi Yang; Jinyi Wang; Eric Decker; David Julian McClements; Lili He

doi:10.1016/j.talanta.2019.120197

Multi-phase detection of antioxidants using surface-enhanced Raman spectroscopy with a gold nanoparticle-coated fiber

Talanta. 2020 Jan 1:206:120197. doi: 10.1016/j.talanta.2019.120197. Epub 2019 Jul 30.

Authors

Qin Tu¹, Zhuangsheng Lin², Jinning Liu², Haochen Dai², Tianxi Yang², Jinyi Wang³, Eric Decker², David Julian McClements², Lili He⁴

Affiliations

¹ College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, PR China; Department of Food Science, University of Massachusetts, Amherst, MA, USA.
² Department of Food Science, University of Massachusetts, Amherst, MA, USA.
³ College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi, 712100, PR China.
⁴ Department of Food Science, University of Massachusetts, Amherst, MA, USA. Electronic address: lilihe@foodsci.umass.edu.

PMID: 31514884
DOI: 10.1016/j.talanta.2019.120197

Abstract

The development of a method for multi-phase detection of antioxidants using surface-enhanced Raman spectroscopy (SERS) with a gold nanoparticle (AuNP)-coated fiber as a substrate is described. The AuNP-coated fiber was directly inserted into a multi-phase system containing model analytes of ascorbic acid, ascorbyl palmitate, and α-tocopherol, representing hydrophilic, amphiphilic, and lipophilic antioxidants, respectively. The AuNP-coated fiber enabled simultaneous detection of antioxidants present within the aqueous, interfacial, and organic phases of the multi-phase system. An oil-in-water emulsion was used as a model multi-phase system, where the antioxidant profiles of the three model analytes were successfully characterized. This method enables rapid, simultaneous, and non-destructive analysis of multiple antioxidants in complex multi-phase systems.

Keywords: Antioxidant; AuNP-Coated fiber; Emulsion; Multi-phase; SERS.