Abstract
Celiac disease is a common form of enteropathy with frequent extraintestinal manifestations (EIM). Misrecognition of these presentations may lead to significant delays in diagnosis. Any organ may be involved, either through an immune/inflammatory phenomenon, or nutritional deficiencies. Some EIM, such as gluten ataxia, may be irreversible if left untreated, but most will improve with a gluten-free diet. Knowledge of the various EIM, as well as the associated conditions which do not improve on a gluten-free diet, will avoid delays in the diagnosis and management of celiac disease and associated manifestations.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Celiac Disease / complications
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Celiac Disease / diagnosis*
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Celiac Disease / diet therapy
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Delayed Diagnosis*
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Diet, Gluten-Free
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Eye Diseases / diagnosis
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Eye Diseases / etiology
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Gastrointestinal Diseases / diagnosis
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Gastrointestinal Diseases / etiology
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Humans
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Malnutrition / diagnosis
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Malnutrition / etiology
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Mental Disorders / diagnosis
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Mental Disorders / etiology
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Mouth Diseases / diagnosis
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Mouth Diseases / etiology
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Musculoskeletal Diseases / diagnosis
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Musculoskeletal Diseases / etiology
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Nervous System Diseases / diagnosis
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Nervous System Diseases / etiology
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Skin Diseases / diagnosis
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Skin Diseases / etiology
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Symptom Assessment*