Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract with a high incidence but a poor therapeutic outcome. However, IBD is generally caused by complicated interactions between environmental factors and gut microflora in genetically susceptible individuals. In view of a series of oral manifestations in patients with IBD and a high detection rate of oral bacteria among this population, oral microbiota may play an important role in the development of IBD. This article reviews the relationship between oral microbiota and IBD.
炎症性肠病（IBD）是一种发病率高但治疗效果欠佳的特发性肠道炎症性疾病。目前认为IBD是环境因素、肠道菌群、个体易感性之间复杂作用的结果。近年来鉴于IBD患者的一系列口腔表征以及口腔微生物在IBD患者体内的高检出率，不少学者认为口腔微生物可能在IBD的发生发展中扮演了重要角色。本文就口腔微生物与IBD的关系研究进展作一综述。.
Keywords: Crohn’s disease; inflammatory bowel disease; oral microbiota; ulcerative colitis.