[Research progress of structured repair of tendon-bone interface]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2019 Sep 15;33(9):1064-1070. doi: 10.7507/1002-1892.201811139.
[Article in Chinese]

Abstract

In sports system, the tendon-bone interface has the effect of tensile and bearing load, so the effect of healing plays a crucial role in restoring joint function. The process of repair is the formation of scar tissue, so it is difficult to achieve the ideal effect for morphology and biomechanical strength. The tissue engineering method can promote the tendon-bone interface healing from the seed cells, growth factors, and scaffolds, and is a new direction in the field of development of the tendon-bone interface healing.

在运动系统中,腱-骨结合部在运动过程中起到抗拉伸、承载负荷的作用,因此其愈合效果在恢复关节功能方面起到至关重要的作用。腱-骨界面损伤修复过程多为瘢痕组织形成,从形态结构和生物力学强度方面难以达到理想效果。而组织工程方法能够从种子细胞、生长因子、支架材料三方面来促进腱-骨愈合效果,是腱-骨愈合发展领域的新方向。.

Keywords: Tendon-bone interface; growth factor; scaffold material; tissue engineering.

Publication types

  • Review

MeSH terms

  • Biomechanical Phenomena
  • Bone and Bones*
  • Humans
  • Tendons*
  • Tissue Engineering* / methods
  • Tissue Engineering* / trends
  • Wound Healing*

Grants and funding

国家自然科学基金资助项目(8157090393)