Recent Advances in Enabling Technologies in 3D Printing for Precision Medicine

Adv Mater. 2020 Apr;32(13):e1902516. doi: 10.1002/adma.201902516. Epub 2019 Sep 12.

Abstract

Advances in areas such as data analytics, genomics, and imaging have revealed individual patient complexities and exposed the inherent limitations of generic therapies for patient treatment. These observations have also fueled the development of precision medicine approaches, where therapies are tailored for the individual rather than the broad patient population. 3D printing is a field that intersects with precision medicine through the design of precision implants with patient-directed shapes, structures, and materials or for the development of patient-specific in vitro models that can be used for screening precision therapeutics. Toward their success, advances in 3D printing and biofabrication technologies are needed with enhanced resolution, complexity, reproducibility, and speed and that encompass a broad range of cells and materials. The overall goal of this progress report is to highlight recent advances in 3D printing technologies that are helping to enable advances important in precision medicine.

Keywords: 3D printing; biofabrication; biomaterials; precision medicine.

Publication types

  • Review

MeSH terms

  • Animals
  • Bioengineering / instrumentation
  • Bioengineering / methods
  • Biomedical Engineering / instrumentation
  • Biomedical Engineering / methods
  • Humans
  • Precision Medicine* / instrumentation
  • Precision Medicine* / methods
  • Printing, Three-Dimensional* / instrumentation
  • Prostheses and Implants