Recent Advances in the Pharmacological Activities of Dioscin

Biomed Res Int. 2019 Aug 14:2019:5763602. doi: 10.1155/2019/5763602. eCollection 2019.

Abstract

Dioscin is a typical saponin with multiple pharmacological activities. The past few years have seen an emerging interest in and growing research on this pleiotropic saponin. Here, we review the emerging pharmacological activities reported recently, with foci on its antitumor, antimicrobial, anti-inflammatory, antioxidative, and tissue-protective properties. The potential use of dioscin in therapies of diverse clinical disorders is also discussed.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Infective Agents / pharmacology
  • Anti-Infective Agents / therapeutic use
  • Anti-Inflammatory Agents / pharmacology
  • Anti-Inflammatory Agents / therapeutic use
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use
  • Antioxidants / pharmacology
  • Antioxidants / therapeutic use
  • Diosgenin / analogs & derivatives*
  • Diosgenin / pharmacology
  • Diosgenin / therapeutic use
  • Humans
  • Saponins / pharmacology
  • Saponins / therapeutic use

Substances

  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Antineoplastic Agents
  • Antioxidants
  • Saponins
  • dioscin
  • Diosgenin