Angiographic characteristics and in hospital outcome of young patients, age up to 40 versus more than 40 years undergoing primary percutaneous coronary intervention

J Pak Med Assoc. 2019 Sep;69(9):1308-1312.

Abstract

Objective: To compare angiographic characteristics and outcomes of primary percutaneous coronary intervention between young and old patients presenting with acute ST Elevation Myocardial Infarction.

Methods: The prospective observational study was conducted at the National Institute of Cardiovascular Diseases, Karachi, from December 17, 2016, to June 16, 2017, and comprised acute ST-Elevation Myocardial Infarction patients undergoing primary percutaneous coronary intervention (PCI). Data was collected on demographic, angiographic, and in-hospital outcomes. Those <40 years were considered young. Data was analysed using SPSS 21.

Results: Of the 415 patients, 50(12%) were young. Proportion of male was higher among the young (p=0.02) and so was the case with positive family history (p=0.002). The young had lesser cases of diabetes (p=0.028) and hypertension (p=0.034). Single vessel disease was more common among young (p<0.001). No significant difference was observed in post-procedure outcome related to age (p>0.05).

Conclusions: Acute Myocardial Infarction in young was more likely associated with male gender, positive family history and less likely with hypertensive and diabetic status.

Keywords: Young, Premature myocardial infarction, Angiographic profile, Primary percutaneous coronary intervention, ST-elevation myocardial infarction.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Chest Pain / etiology
  • Comorbidity
  • Coronary Angiography
  • Coronary Disease
  • Diabetes Mellitus / epidemiology
  • Dyspnea / etiology
  • Female
  • Hospital Mortality*
  • Humans
  • Hypertension / epidemiology
  • Length of Stay / statistics & numerical data
  • Male
  • Medical History Taking
  • Middle Aged
  • Percutaneous Coronary Intervention*
  • Postoperative Complications / epidemiology*
  • Prospective Studies
  • ST Elevation Myocardial Infarction / complications
  • ST Elevation Myocardial Infarction / diagnostic imaging
  • ST Elevation Myocardial Infarction / epidemiology
  • ST Elevation Myocardial Infarction / surgery*
  • Sex Distribution
  • Young Adult