Educational and health outcomes associated with bronchopulmonary dysplasia in 15-year-olds born preterm

PLoS One. 2019 Sep 11;14(9):e0222286. doi: 10.1371/journal.pone.0222286. eCollection 2019.

Abstract

Introduction: To evaluate the consequences of bronchopulmonary dysplasia (BPD) on academic outcomes and healthcare use in adolescents born very preterm.

Methods: This cohort study included 15-year-old adolescents born very preterm (< 32 weeks) between 2011 and 2013, with and without BPD, and controls born full term. Data regarding academic performance, current medical follow-up, and family characteristics were collected. Multivariate logistic regression was used to quantify relationships between academic outcomes and BPD.

Results: From the 1341 children included in the initial cohort, 985 adolescents were eligible and 351 included (55 preterms with a history of BPD, 249 without, and 47 controls). Among adolescents born very preterm, a history of BPD was associated with a higher risk to attend a school for children with special needs (p < 0.05) and to have repeated a grade (p = 0.01). It was also associated with an increased number of medical and paramedical consultations. A history of BPD was not associated with the parents' employment status, family structure, or the presence of younger siblings.

Conclusion: This study highlights that a history of BPD is associated with poorer academic outcomes and high healthcare use in adolescence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Academic Success
  • Adolescent
  • Bronchopulmonary Dysplasia / complications*
  • Bronchopulmonary Dysplasia / epidemiology
  • Bronchopulmonary Dysplasia / mortality*
  • Cohort Studies
  • Female
  • France
  • Humans
  • Infant, Newborn
  • Male
  • Patient Acceptance of Health Care / psychology
  • Pregnancy
  • Premature Birth / psychology*

Grants and funding

The EPIPAGEADO study was sponsored by the Assistance Publique-Hôpitaux de Paris (Département de la Recherche Clinique et de Développement). The study was funded by a grant from the Programme Hospitalier de Recherche Clinique (PHRC) 2010 (Ministère de la Santé, N°AOM P100117). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.