Are thyroid function tests in neonates born to mothers with hypothyroidism clinically useful?

Foteini Balomenou; Ekaterini Siomou; Georgios Kolios; Eleni Bairaktari; Meropi Tzoufi; Vasileios Giapros

doi:10.1016/j.earlhumdev.2019.104877

Are thyroid function tests in neonates born to mothers with hypothyroidism clinically useful?

Early Hum Dev. 2019 Dec:139:104877. doi: 10.1016/j.earlhumdev.2019.104877. Epub 2019 Sep 7.

Authors

Foteini Balomenou¹, Ekaterini Siomou¹, Georgios Kolios², Eleni Bairaktari², Meropi Tzoufi¹, Vasileios Giapros³

Affiliations

¹ University of Ioannina, Child Health Department, Greece.
² University of Ioannina, Biochemistry Department, Greece.
³ University of Ioannina, Child Health Department, Greece. Electronic address: vgiapros@uoi.gr.

PMID: 31505311
DOI: 10.1016/j.earlhumdev.2019.104877

Abstract

Thyroid function tests from all babies born to mothers with hypothyroidism (381 neonates) during a 6-year period, were collected and examined against findings of the universal screening test. No difference was found between the results of bloodspot test and later blood test. Additional blood tests for thyroid function in this population of neonates seem to be without clinical value and may be discontinued.

Keywords: Congenital hypothyroidism; Gestational hypothyroidism; Neonates; TSH; Thyroid function tests.

MeSH terms

Female
Humans
Hypothyroidism*
Infant, Newborn
Infant, Premature
Infant, Small for Gestational Age
Mothers
Pregnancy
Pregnancy Complications / etiology*
Retrospective Studies
Thyroid Function Tests*
Thyrotropin / blood*

Substances

Thyrotropin