Considerations for neonatal and pediatric pain management

Am J Health Syst Pharm. 2019 Sep 16;76(19):1511-1520. doi: 10.1093/ajhp/zxz166.

Abstract

Purpose: Current literature and clinical practice guidelines on pediatric pain management are reviewed.

Summary: Acute pain is commonly present in neonatal and pediatric patients due to underlying disease states or procedures. Especially in institutions with limited pediatric pain services, it is imperative to describe the appropriate management of pain and pharmacotherapy options that are effective and safe in pediatric patients. Despite the knowledge of pain being an important aspect in the management of children, barriers exist, leading to suboptimal treatment. Addressing these barriers through education of healthcare practitioners, families, and patients will lead to optimizing the patient pain experience. Tools for pain assessment vary depending on the type of pain, the child's age and understanding of pain, and the clinical situation. Pharmacotherapy options for pain management in neonates and pediatric patients include opioid and nonopioid agents. Efficacy and safety data on the use of medications for the treatment of pain in pediatric patients is described. The delivery of medication encompasses patient-specific factors and preferences. Strategies for opioid stewardship and management of iatrogenic withdrawal pose a unique challenge in pediatric patients.

Conclusion: The management of acute pain in neonates and pediatric patients should be a priority for all practitioners caring for these patients. Use of age-appropriate pain assessment tools and understanding of the mechanisms of action and roles in therapy of various nonopioid and opioid therapies can help optimize treatment of pain in neonatal and pediatric patients.

Keywords: assessment, analgesia; opioid-related disorders/prevention and control; opioids; pediatrics.

Publication types

  • Review

MeSH terms

  • Acute Pain / diagnosis
  • Acute Pain / drug therapy*
  • Age Factors
  • Analgesics / pharmacology*
  • Analgesics / therapeutic use
  • Child
  • Child, Preschool
  • Dose-Response Relationship, Drug
  • Humans
  • Infant, Newborn
  • Medication Therapy Management / standards*
  • Pain Management / methods
  • Pain Management / standards*
  • Pain Measurement / methods
  • Pain Measurement / standards*
  • Patient Education as Topic
  • Practice Guidelines as Topic

Substances

  • Analgesics