Hydrothermal-assisted synthesis of highly crystalline titania-copper oxide binary systems with enhanced antibacterial properties

Abstract

Binary oxide systems containing TiO₂ and CuO were synthesized using hydrothermal treatment and shown to have enhanced antibacterial properties. A detailed investigation was made of the effect of the molar ratio of components (TiO₂:CuO = 7:3, 5:5, 3:7, 1:9) on the physicochemical parameters and antibacterial activity. Analysis of morphology (SEM, TEM and HRTEM) confirmed the presence of spherical and sheet-shaped particles. On the XRD patterns for the binary oxide materials, two crystalline forms (anatase and monoclinic CuO) were observed. It was found that an increase in CuO content led to a decrease in the BET surface area of the TiO₂-CuO binary oxide systems. The synthesized TiO₂-CuO materials exhibited very good antibacterial activity against both Gram-positive (methicillin-resistant Staphylococcus aureus and Bacillus cereus) and Gram-negative (Salmonella Enteritidis and Pseudomonas aeruginosa) bacteria. The obtained results show that TiO₂-CuO oxide materials may have applications in the biomedical and food industries.

Keywords: Antibacterial activity; Copper oxide; Hydrothermal synthesis; TiO(2)-CuO binary oxide systems; Titania.