Intraocular pressure in patients with human immunodeficiency virus, correlation with TCD4, viral load and demographic characteristics: a case-control study

Leonardo Medlig de Sousa Cravo; Ana Luiza Biancardi; Thamiles Batista Ronconi; Vinicius Layter Xavier; Haroldo Moraes Jr

doi:10.2147/OPTH.S216759

Intraocular pressure in patients with human immunodeficiency virus, correlation with TCD4, viral load and demographic characteristics: a case-control study

Clin Ophthalmol. 2019 Aug 5:13:1477-1483. doi: 10.2147/OPTH.S216759. eCollection 2019.

Authors

Leonardo Medlig de Sousa Cravo¹, Ana Luiza Biancardi², Thamiles Batista Ronconi³, Vinicius Layter Xavier⁴, Haroldo Moraes Jr⁵

Affiliations

¹ Postgraduate Surgical Sciences, Hospital Universitário da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil.
² Uveitis Ophthalmology Department, Hospital Universitário da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil.
³ Dermatology, Hospital Universitário da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil.
⁴ Statistics Department, Institute of Mathematics and Statistics, Universidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ 20550-900, Brazil.
⁵ Department of Ophthalmology, Hospital Universitário Da Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-590, Brazil.

Abstract

Purpose: To compare if patients with HIV have lower intraocular pressure than patients without HIV.

Methods: The association of intraocular pressure corrected by pachymetry and the relationship with viral load (VL) and TCD4 cells was studied. A total of 99 patients with HIV (91 who were on regular treatment and in control of the disease - group 1; and 8 who were without treatment - group 2) and 100 controls were studied.

Results: Only age was of statistical significance; the group with HIV without control of the disease was the youngest. There was a decrease of -1.54 mmHg in the IOP of group 1 in relation to the controls and -3.63 mmHg in the IOP of group 2 in relation to the controls.

Conclusion: HIV patients had lower IOP than the control population. However, the relationship between IOP, VL and TCD4 was not found.

Keywords: HIV; acquired immunodeficiency syndrome; intraocular pressure; ophthalmopathy.