Topical biomaterials to prevent post-tonsillectomy hemorrhage

J Otolaryngol Head Neck Surg. 2019 Sep 6;48(1):45. doi: 10.1186/s40463-019-0368-1.

Abstract

Despite advances in surgical technique, postoperative hemorrhage remains a common cause of mortality and morbidity for patients following tonsillectomy. Application of biomaterials at the time of tonsillectomy can potentially accelerate mucosal wound healing and eliminate the risk of post-tonsillectomy hemorrhage (PTH). To understand the current state and identify possible routes for the development of the ideal biomaterials to prevent PTH, topical biomaterials for eliminating the risk of PTH were reviewed. Alternative topical biomaterials that hold the potential to reduce the risk of PTH were also summarized.

Keywords: Biomaterial; Post-tonsillectomy hemorrhage; Surgical hemostasis; Tonsillectomy; Topical.

Publication types

  • Review

MeSH terms

  • Antifibrinolytic Agents
  • Biocompatible Materials* / chemistry
  • Fibrin Tissue Adhesive
  • Hemostasis, Surgical / methods
  • Humans
  • Postoperative Hemorrhage / prevention & control*
  • Tonsillectomy / adverse effects*

Substances

  • Antifibrinolytic Agents
  • Biocompatible Materials
  • Fibrin Tissue Adhesive