Since the discovery of stripe order in La1.6-x Nd0.4Sr x CuO4 superconductors in 1995, charge ordering in cuprate superconductors has been intensively studied by various experimental techniques. Among these studies, scanning tunneling microscope (STM) plays an irreplaceable role in determining the real space structures of charge ordering. STM imaging of different families of cuprates over a wide range of doping levels reveal similar checkerboard-like patterns, indicating that such a charge ordered state is likely a ubiquitous and intrinsic characteristic of cuprate superconductors, which may shed light on understanding the mechanism of high-temperature superconductivity. In another class of high-temperature superconductors, iron-based superconductors, STM studies reveal several charge ordered states as well, but their real-space patterns and the interplay with superconductivity are markedly different among different materials. In this paper, we present a brief review on STM studies of charge ordering in these two classes of high-temperature superconductors. Possible origins of charge ordering and its interplay with superconductivity will be discussed.