Chewed or Crushed Administration of Adenosine Diphosphate Receptor Inhibitors in Acute Coronary Syndromes: a Systematic Review and Meta-analysis of Randomized Controlled Trials

Cardiovasc Drugs Ther. 2020 Feb;34(1):139-142. doi: 10.1007/s10557-019-06905-w.

Authors

Hourmazd Haghbayan^{1

2}, Bishoy Deif³, Eric A Coomes⁴

Affiliations

¹ Division of Cardiology, University Hospital, London Health Sciences Centre, Western University, Room C6-004, 339 Windermere Road, London, Ontario, N6A 5A5, Canada. hourmazd.haghbayan@mail.utoronto.ca.
² Department of Social and Preventive Medicine, Université Laval, Quebec City, Québec, Canada. hourmazd.haghbayan@mail.utoronto.ca.
³ Division of Cardiology, University Hospital, London Health Sciences Centre, Western University, Room C6-004, 339 Windermere Road, London, Ontario, N6A 5A5, Canada.
⁴ Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

PMID: 31485881
DOI: 10.1007/s10557-019-06905-w

No abstract available

Publication types

Letter
Meta-Analysis
Systematic Review

MeSH terms

Acute Coronary Syndrome / blood
Acute Coronary Syndrome / diagnosis
Acute Coronary Syndrome / therapy*
Administration, Oral
Female
Humans
Male
Middle Aged
Percutaneous Coronary Intervention* / adverse effects
Platelet Aggregation Inhibitors / administration & dosage*
Platelet Aggregation Inhibitors / adverse effects
Platelet Aggregation Inhibitors / pharmacokinetics
Prasugrel Hydrochloride / administration & dosage*
Prasugrel Hydrochloride / adverse effects
Prasugrel Hydrochloride / pharmacokinetics
Purinergic P2 Receptor Antagonists / administration & dosage*
Purinergic P2 Receptor Antagonists / adverse effects
Purinergic P2 Receptor Antagonists / pharmacokinetics
Randomized Controlled Trials as Topic
Tablets
Ticagrelor / administration & dosage*
Ticagrelor / adverse effects
Ticagrelor / pharmacokinetics
Treatment Outcome

Substances

Platelet Aggregation Inhibitors
Purinergic P2 Receptor Antagonists
Tablets
Prasugrel Hydrochloride
Ticagrelor