Concordance of p16, FH, and alpha-SMA expression with the fumarate hydratase gene mutational status in sporadic and hereditary piloleiomyomas

Pathology. 2019 Oct;51(6):659-663. doi: 10.1016/j.pathol.2019.05.006. Epub 2019 Aug 31.

Authors

Laura Cristina Gironi¹, Lara Camillo², Francesca Zottarelli²; Leiomyomatosis Interdisciplinary Group; Paola Savoia²

Collaborators

Leiomyomatosis Interdisciplinary Group:
Pamela Farinelli³, Paolo Spina³, Irma Dianzani³, Renzo Luciano Boldorini³, Guido Valente³, Enrico Colombo³, Barbara Pasini⁴, Paola Ogliara⁴, Francesca Restivo⁴

Affiliations

¹ Department of Health Sciences, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy. Electronic address: gironi.laura@gmail.com.
² Department of Health Sciences, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.
³ Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.
⁴ University of Turin, Turin, Italy.

PMID: 31481265
DOI: 10.1016/j.pathol.2019.05.006

No abstract available

Publication types

Letter

MeSH terms

Actins / metabolism
Adult
Cyclin-Dependent Kinase Inhibitor p16 / metabolism
DNA Mutational Analysis
Female
Fumarate Hydratase / genetics*
Gene Expression Regulation, Neoplastic*
Genotype
Germ-Line Mutation
Heterozygote
Humans
Leiomyoma / genetics*
Leiomyoma / metabolism
Leiomyoma / pathology
Male
Middle Aged
Mutation
Skin Neoplasms / genetics*
Skin Neoplasms / metabolism
Skin Neoplasms / pathology

Substances

ACTA2 protein, human
Actins
CDKN2A protein, human
Cyclin-Dependent Kinase Inhibitor p16
Fumarate Hydratase