Outcomes of extended-spectrum beta-lactamases producing Enterobacteriaceae colonization among patients abdominal surgery patients

Infect Control Hosp Epidemiol. 2019 Nov;40(11):1290-1293. doi: 10.1017/ice.2019.254. Epub 2019 Sep 4.

Abstract

Preoperative enteric screening for extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae was conducted in 360 patients prospectively observed for surgical site infection (SSI). ESBL colonization (adjusted odds ratio [aOR], 2.4) and dirty wound classification (aOR, 3.6) were associated with SSI; no association between carbapenem prophylaxis and reduction in SSI was detected.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdomen / surgery
  • Adolescent
  • Adult
  • Carbapenems / therapeutic use
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae / isolation & purification
  • Enterobacteriaceae Infections / drug therapy
  • Enterobacteriaceae Infections / epidemiology*
  • Enterobacteriaceae Infections / microbiology
  • Female
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / microbiology
  • Postoperative Complications / prevention & control
  • Prospective Studies
  • Risk Factors
  • Surgical Wound Infection / epidemiology*
  • Surgical Wound Infection / microbiology
  • Surgical Wound Infection / prevention & control
  • Thailand / epidemiology
  • Young Adult
  • beta-Lactamases / metabolism

Substances

  • Carbapenems
  • beta-Lactamases